Igor Kurinov: search on Z-Library

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1

Insights into anaphase promoting complex TPR subdomain assembly from a CDC26–APC6 structure

Wang, Jing, Dye, Billy T, Rajashankar, Kanagalaghatta R, Kurinov, Igor, Schulman, Brenda A

Journal:

Nature Structural and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 520 KB

english, 2009

2

Implementation of a k/k0 Method to Identify Long-Range Structure in Transition States during Conformational Folding/Unfolding of Proteins

Lovy Pradeep, Igor Kurinov, Steven E. Ealick, Harold A. Scheraga

Journal:

Year:

2007

Language:

english

File:

PDF, 1.41 MB

english, 2007

3

High resolution X-ray structure of potent anti-HIV pokeweed antiviral protein-III

Igor V Kurinov, Fatih M Uckun

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 431 KB

english, 2003

4

Deguanylation of Human Immunodeficiency Virus (HIV-1) RNA by Recombinant Pokeweed Antiviral Protein

Francis Rajamohan, Igor V. Kurinov, Taracad K. Venkatachalam, Fatih M. Uckun

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 231 KB

english, 1999

5

The Crystal Structure of the Active Form of the C-Terminal Kinase Domain of Mitogen- and Stress-Activated Protein Kinase 1

Margarita Malakhova, Igor D'Angelo, Hong-Gyum Kim, Igor Kurinov, Ann M. Bode, Zigang Dong

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

6

Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway

Asad M. Taherbhoy, Stephen W. Tait, Stephen E. Kaiser, Allison H. Williams, Alan Deng, Amanda Nourse, Michal Hammel, Igor Kurinov, Charles O. Rock, Douglas R. Green, Brenda A. Schulman

Journal:

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

7

Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures

Kaiser, Stephen E, Mao, Kai, Taherbhoy, Asad M, Yu, Shanshan, Olszewski, Jennifer L, Duda, David M, Kurinov, Igor, Deng, Alan, Fenn, Timothy D, Klionsky, Daniel J, Schulman, Brenda A

Journal:

Nature Structural and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 2.34 MB

english, 2012

8

Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism

Duda, David M., Olszewski, Jennifer L., Schuermann, Jonathan P., Kurinov, Igor, Miller, Darcie J., Nourse, Amanda, Alpi, Arno F., Schulman, Brenda A.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.33 MB

english, 2013

9

Increased Hydroxyl Radical Production and Apoptosis in PC12 Neuron Cells Expressing the Gain-of-Function Mutant G93A SOD1 Gene

Rugao Liu, Rama Krishna Narla, Igor Kurinov, Baolin Li and Fatih M. Uckun

Journal:

Radiation Research

Year:

1999

Language:

english

File:

PDF, 3.10 MB

english, 1999

10

Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation

Huo, Yanwu, Nam, Ki Hyun, Ding, Fang, Lee, Heejin, Wu, Lijie, Xiao, Yibei, Farchione, M Daniel, Zhou, Sharleen, Rajashankar, Kanagalaghatta, Kurinov, Igor, Zhang, Rongguang, Ke, Ailong

Journal:

Nature Structural and Molecular Biology

Year:

2014

Language:

english

File:

PDF, 1.98 MB

english, 2014

11

Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors

Sanches, Mario, Duffy, Nicole M., Talukdar, Manisha, Thevakumaran, Nero, Chiovitti, David, Canny, Marella D., Lee, Kenneth, Kurinov, Igor, Uehling, David, Al-awar, Rima, Poda, Gennadiy, Prakesch, Mich

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.72 MB

english, 2014

12

A Localized Specific Interaction Alters the Unfolding Pathways of Structural Homologues

Xu, Guoqiang, Narayan, Mahesh, Kurinov, Igor, Ripoll, Daniel R., Welker, Ervin, Khalili, Mey, Ealick, Steven E., Scheraga, Harold A.

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 399 KB

english, 2006

13

Drug-Resistant HIV-1 Proteases Identify Enzyme Residues Important for Substrate Selection and Catalytic Rate †

Ridky, Todd W., Kikonyogo, Alexandra, Leis, Jonathan, Gulnik, Sergei, Copeland, Terry, Erickson, John, Wlodawer, Alexander, Kurinov, Igor, Harrison, Robert W., Weber, Irene T.

Journal:

Year:

1998

Language:

english

File:

PDF, 87 KB

english, 1998

14

A RING E3–substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases

Calabrese, Matthew F, Scott, Daniel C, Duda, David M, Grace, Christy R R, Kurinov, Igor, Kriwacki, Richard W, Schulman, Brenda A

Journal:

Nature Structural and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 727 KB

english, 2011

15

Higher-Order Assembly of BRCC36–KIAA0157 Is Required for DUB Activity and Biological Function

Zeqiraj, Elton, Tian, Lei, Piggott, Christopher A., Pillon, Monica C., Duffy, Nicole M., Ceccarelli, Derek F., Keszei, Alexander F.A., Lorenzen, Kristina, Kurinov, Igor, Orlicky, Stephen, Gish, Gerald

Journal:

Year:

2015

Language:

english

File:

PDF, 4.77 MB

english, 2015

16

Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1–F-box interface

Gorelik, Maryna, Orlicky, Stephen, Sartori, Maria A., Tang, Xiaojing, Marcon, Edyta, Kurinov, Igor, Greenblatt, Jack F., Tyers, Mike, Moffat, Jason, Sicheri, Frank, Sidhu, Sachdev S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.44 MB

english, 2016

17

Structural and functional characterization of KEOPS dimerization by Pcc1 and its role in t 6 A biosynthesis

Wan, Leo C.K., Pillon, Monica C., Thevakumaran, Neroshan, Sun, Yulong, Chakrabartty, Avi, Guarné, Alba, Kurinov, Igor, Durocher, Daniel, Sicheri, Frank

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 3.54 MB

english, 2016

18

MOB1 mediated phospho-recognition in the core mammalian Hippo pathway

Couzens, Amber L., Xiong, Shawn, Knight, James DR, Mao, Daniel Y, Guettler, Sebastian, Picaud, Sarah, Kurinov, Igor, Filippakopoulos, Panagis, Sicheri, Frank, Gingras, Anne-Claude

Journal:

Molecular & Cellular Proteomics

Year:

2017

Language:

english

File:

PDF, 2.23 MB

english, 2017

19

Regulation of protein interactions by MOB1 phosphorylation

Xiong, Shawn, Couzens, Amber L, Kean, Michelle J, Mao, Daniel Y, Guettler, Sebastian, Kurinov, Igor, Gingras, Anne-Claude, Sicheri, Frank

Journal:

Molecular & Cellular Proteomics

Year:

2017

Language:

english

File:

PDF, 1.94 MB

english, 2017

20

Crystal structure of the human Polϵ B-subunit in complex with the C-terminal domain of the catalytic subunit

Baranovskiy, Andrey G, Gu, Jianyou, Babayeva, Nigar D, Kurinov, Igor, Pavlov, Youri I, Tahirov, Tahir H

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 8.79 MB

english, 2017

21

Effects of rigidity on the selectivity of protein kinase inhibitors

Assadieskandar, Amir, Yu, Caiqun, Maisonneuve, Pierre, Liu, Xu, Chen, Ying-Chu, Prakash, G.K. Surya, Kurinov, Igor, Sicheri, Frank, Zhang, Chao

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.33 MB

english, 2018

22

MEK drives BRAF activation through allosteric control of KSR proteins

Lavoie, Hugo, Sahmi, Malha, Maisonneuve, Pierre, Marullo, Sara A., Thevakumaran, Neroshan, Jin, Ting, Kurinov, Igor, Sicheri, Frank, Therrien, Marc

Journal:

Year:

2018

Language:

english

File:

PDF, 11.85 MB

english, 2018

23

Structural Insights into the Induced-fit Inhibition of Fascin by a Small-Molecule Inhibitor

Huang, Jianyun, Dey, Raja, Wang, Yufeng, Jakoncic, Jean, Kurinov, Igor, Huang, Xin-Yun

Journal:

Journal of Molecular Biology

Year:

2018

Language:

english

File:

PDF, 2.33 MB

english, 2018

24

Structure of human ADP-ribosyl-acceptor hydrolase 3 bound to ADP-ribose reveals a conformational switch that enables specific substrate recognition

Pourfarjam, Yasin, Ventura, Jessica, Kurinov, Igor, Cho, Ahra, Moss, Joel, Kim, In-Kwon

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 1.60 MB

english, 2018

25

Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment

Xiong, Shawn, Lorenzen, Kristina, Couzens, Amber L., Templeton, Catherine M., Rajendran, Dushyandi, Mao, Daniel Y.L., Juang, Yu-Chi, Chiovitti, David, Kurinov, Igor, Guettler, Sebastian, Gingras, Anne

Journal:

Year:

2018

Language:

english

File:

PDF, 5.05 MB

english, 2018

26

A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases

Gorelik, Maryna, Manczyk, Noah, Pavlenco, Alevtina, Kurinov, Igor, Sidhu, Sachdev S., Sicheri, Frank

Journal:

Year:

2018

Language:

english

File:

PDF, 3.05 MB

english, 2018

27

FAM105A/OTULINL Is a Pseudodebuiquitinase of the OTU-Class that Localizes to the ER Membrane

Ceccarelli, Derek F., Ivantsiv, Sofiia, Mullin, Amber Anne, Coyaud, Etienne, Manczyk, Noah, Maisonneuve, Pierre, Kurinov, Igor, Zhao, Liang, Go, Chris, Gingras, Anne-Claude, Raught, Brian, Cordes, Sab

Journal:

Year:

2019

Language:

english

File:

PDF, 8.29 MB

english, 2019

28

Rigidification Dramatically Improves Inhibitor Selectivity for RAF Kinases

Assadieskandar, Amir, Yu, Caiqun, Maisonneuve, Pierre, Kurinov, Igor, Sicheri, Frank, Zhang, Chao

Journal:

ACS Medicinal Chemistry Letters

Year:

2019

Language:

english

File:

PDF, 1.25 MB

english, 2019

29

Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids

Wiechmann, Svenja, Maisonneuve, Pierre, Grebbin, Britta Moyo, Hoffmeister, Meike, Kaulich, Manuel, Clevers, Hans, Rajalingam, Krishnaraj, Kurinov, Igor, Farin, Henner F., Sicheri, Frank, Ernst, Andrea

Journal:

Journal of Biological Chemistry

Year:

2020

Language:

english

File:

PDF, 5.25 MB

english, 2020